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    BMCBI
    2010
    90views more  BMCBI 2010»
    Local alignment of generalized k-base encoded DNA sequence
    14 years 10 months ago
    Local alignment of generalized k-base encoded DNA sequence
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    Background: DNA sequence comparison is a well-studied problem, in which two DNA sequences are compared using a weighted edit distance. Recent DNA sequencing technologies however o...
    Nils Homer, Stanley F. Nelson, Barry Merriman
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    BMCBI
    2010
    109views more  BMCBI 2010»
    Predicting gene function using hierarchical multi-label decision tree ensembles
    14 years 10 months ago
    Predicting gene function using hierarchical multi-label decision tree ensembles
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    Background: S. cerevisiae, A. thaliana and M. musculus are well-studied organisms in biology and the sequencing of their genomes was completed many years ago. It is still a challe...
    Leander Schietgat, Celine Vens, Jan Struyf, Hendri...
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    BMCBI
    2010
    115views more  BMCBI 2010»
    Multiconstrained gene clustering based on generalized projections
    14 years 10 months ago
    Multiconstrained gene clustering based on generalized projections
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    Background: Gene clustering for annotating gene functions is one of the fundamental issues in bioinformatics. The best clustering solution is often regularized by multiple constra...
    Jia Zeng, Shanfeng Zhu, Alan Wee-Chung Liew, Hong ...
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    BMCBI
    2010
    99views more  BMCBI 2010»
    Different effects of the probe summarization algorithms PLIER and RMA on high-level analysis of Affymetrix exon arrays
    14 years 10 months ago
    Different effects of the probe summarization algorithms PLIER and RMA on high-level analysis of Affymetrix exon arrays
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    Background: Alternative splicing is an important mechanism that increases protein diversity and functionality in higher eukaryotes. Affymetrix exon arrays are a commercialized pla...
    Yi Qu, Fei He, Yuchen Chen
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    BMCBI
    2010
    151views more  BMCBI 2010»
    Classification of G-protein coupled receptors based on support vector machine with maximum relevance minimum redundancy and gene
    14 years 10 months ago
    Classification of G-protein coupled receptors based on support vector machine with maximum relevance minimum redundancy and gene
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    Background: Because a priori knowledge about function of G protein-coupled receptors (GPCRs) can provide useful information to pharmaceutical research, the determination of their ...
    Zhanchao Li, Xuan Zhou, Zong Dai, Xiaoyong Zou
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