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295views
14 years 2 months ago
The Age of Analog Networks.
A large class of systems of biological and technological relevance can be described as analog networks, that is, collections of dynamic devices interconnected by links of varying s...
Claudio Mattiussi, Daniel Marbach, Peter Dürr, Da...
BMCBI
2008
132views more  BMCBI 2008»
15 years 4 months ago
The Average Mutual Information Profile as a Genomic Signature
Background: Occult organizational structures in DNA sequences may hold the key to understanding functional and evolutionary aspects of the DNA molecule. Such structures can also p...
Mark Bauer, Sheldon M. Schuster, Khalid Sayood
HICSS
2003
IEEE
98views Biometrics» more  HICSS 2003»
15 years 9 months ago
On the Limits of Bottom-Up Computer Simulation: Towards a Nonlinear Modeling Culture
1 In the complexity and simulation communities there is growing support for the use of bottom-up computer-based simulation in the analysis of complex systems. The presumption is th...
Kurt A. Richardson
CORR
2010
Springer
127views Education» more  CORR 2010»
15 years 4 months ago
Statistical and Computational Tradeoffs in Stochastic Composite Likelihood
Maximum likelihood estimators are often of limited practical use due to the intensive computation they require. We propose a family of alternative estimators that maximize a stoch...
Joshua Dillon, Guy Lebanon
RECOMB
2002
Springer
16 years 4 months ago
A Survey of Computational Methods for Determining Haplotypes
It is widely anticipated that the study of variation in the human genome will provide a means of predicting risk of a variety of complex diseases. Single nucleotide polymorphisms (...
Bjarni V. Halldórsson, Vineet Bafna, Nathan...