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BMCBI
2010
132views more  BMCBI 2010»
15 years 3 months ago
Error margin analysis for feature gene extraction
Background: Feature gene extraction is a fundamental issue in microarray-based biomarker discovery. It is normally treated as an optimization problem of finding the best predictiv...
Chi Kin Chow, Hai Long Zhu, Jessica Lacy, Winston ...
BMCBI
2010
154views more  BMCBI 2010»
15 years 3 months ago
An eScience-Bayes strategy for analyzing omics data
Background: The omics fields promise to revolutionize our understanding of biology and biomedicine. However, their potential is compromised by the challenge to analyze the huge da...
Martin Eklund, Ola Spjuth, Jarl E. S. Wikberg
BMCBI
2010
183views more  BMCBI 2010»
15 years 3 months ago
SING: Subgraph search In Non-homogeneous Graphs
Background: Finding the subgraphs of a graph database that are isomorphic to a given query graph has practical applications in several fields, from cheminformatics to image unders...
Raffaele Di Natale, Alfredo Ferro, Rosalba Giugno,...
BMCBI
2010
109views more  BMCBI 2010»
15 years 3 months ago
Predicting gene function using hierarchical multi-label decision tree ensembles
Background: S. cerevisiae, A. thaliana and M. musculus are well-studied organisms in biology and the sequencing of their genomes was completed many years ago. It is still a challe...
Leander Schietgat, Celine Vens, Jan Struyf, Hendri...
BMCBI
2010
110views more  BMCBI 2010»
15 years 3 months ago
On the use of resampling tests for evaluating statistical significance of binding-site co-occurrence
Background: In eukaryotes, most DNA-binding proteins exert their action as members of large effector complexes. The presence of these complexes are revealed in high-throughput gen...
David S. Huen, Steven Russell
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