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180
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BMCBI
2011
14 years 10 months ago
Motif-guided sparse decomposition of gene expression data for regulatory module identification
Background: Genes work coordinately as gene modules or gene networks. Various computational approaches have been proposed to find gene modules based on gene expression data; for e...
Ting Gong, Jianhua Xuan, Li Chen, Rebecca B. Riggi...
139
Voted
BMCBI
2011
14 years 10 months ago
Meta-analysis of gene expression microarrays with missing replicates
Background: Many different microarray experiments are publicly available today. It is natural to ask whether different experiments for the same phenotypic conditions can be combin...
Fan Shi, Gad Abraham, Christopher Leckie, Izhak Ha...
153
Voted
BMCBI
2011
14 years 10 months ago
pROC: an open-source package for R and S+ to analyze and compare ROC curves
Background: Receiver operating characteristic (ROC) curves are useful tools to evaluate classifiers in biomedical and bioinformatics applications. However, conclusions are often r...
Xavier Robin, Natacha Turck, Alexandre Hainard, Na...
168
Voted
BMCBI
2011
14 years 10 months ago
Classification of viral zoonosis through receptor pattern analysis
Background: Viral zoonosis, the transmission of a virus from its primary vertebrate reservoir species to humans, requires ubiquitous cellular proteins known as receptor proteins. ...
Se-Eun Bae, Hyeon Seok Son
158
Voted
BMCBI
2011
14 years 10 months ago
Detection of viral sequence fragments of HIV-1 subfamilies yet unknown
Background: Methods of determining whether or not any particular HIV-1 sequence stems - completely or in part - from some unknown HIV-1 subtype are important for the design of vac...
Thomas Unterthiner, Anne-Kathrin Schultz, Jan Bull...
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