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77
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BIB
2006
172views more  BIB 2006»
14 years 9 months ago
Advances in the Exon-Intron Database (EID)
Investigation of exon^intron gene structures is a non-trivial task due to enormous expansions of the eukaryotic genomes, great variety of gene forms, and the imperfectness in sequ...
Valery Shepelev, Alexei Fedorov
BMCBI
2006
239views more  BMCBI 2006»
14 years 9 months ago
Applying dynamic Bayesian networks to perturbed gene expression data
Background: A central goal of molecular biology is to understand the regulatory mechanisms of gene transcription and protein synthesis. Because of their solid basis in statistics,...
Norbert Dojer, Anna Gambin, Andrzej Mizera, Bartek...
BMCBI
2006
90views more  BMCBI 2006»
14 years 9 months ago
A Fourier Transformation based Method to Mine Peptide Space for Antimicrobial Activity
Background: Naturally occurring antimicrobial peptides are currently being explored as potential candidate peptide drugs. Since antimicrobial peptides are part of the innate immun...
Vijayaraj Nagarajan, Navodit Kaushik, Beddhu Mural...
98
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BMCBI
2006
139views more  BMCBI 2006»
14 years 9 months ago
Improvement in accuracy of multiple sequence alignment using novel group-to-group sequence alignment algorithm with piecewise li
Background: Multiple sequence alignment (MSA) is a useful tool in bioinformatics. Although many MSA algorithms have been developed, there is still room for improvement in accuracy...
Shinsuke Yamada, Osamu Gotoh, Hayato Yamana
85
Voted
BMCBI
2006
136views more  BMCBI 2006»
14 years 9 months ago
EMD: an ensemble algorithm for discovering regulatory motifs in DNA sequences
Background: Understanding gene regulatory networks has become one of the central research problems in bioinformatics. More than thirty algorithms have been proposed to identify DN...
Jianjun Hu, Yifeng D. Yang, Daisuke Kihara