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BMCBI
2006
121views more  BMCBI 2006»
15 years 4 months ago
Splice site identification using probabilistic parameters and SVM classification
Background: Recent advances and automation in DNA sequencing technology has created a vast amount of DNA sequence data. This increasing growth of sequence data demands better and ...
A. K. M. A. Baten, Bill C. H. Chang, Saman K. Halg...
BMCBI
2006
142views more  BMCBI 2006»
15 years 4 months ago
Improving the Performance of SVM-RFE to Select Genes in Microarray Data
Background: Recursive Feature Elimination is a common and well-studied method for reducing the number of attributes used for further analysis or development of prediction models. ...
Yuanyuan Ding, Dawn Wilkins
BMCBI
2006
101views more  BMCBI 2006»
15 years 4 months ago
How repetitive are genomes?
Background: Genome sequences vary strongly in their repetitiveness and the causes for this are still debated. Here we propose a novel measure of genome repetitiveness, the index o...
Bernhard Haubold, Thomas Wiehe
BMCBI
2006
113views more  BMCBI 2006»
15 years 4 months ago
QualitySNP: a pipeline for detecting single nucleotide polymorphisms and insertions/deletions in EST data from diploid and polyp
Background: Single nucleotide polymorphisms (SNPs) are important tools in studying complex genetic traits and genome evolution. Computational strategies for SNP discovery make use...
Jifeng Tang, Ben Vosman, Roeland E. Voorrips, C. G...
BMCBI
2006
108views more  BMCBI 2006»
15 years 4 months ago
Probe set algorithms: is there a rational best bet?
Affymetrix microarrays have become a standard experimental platform for studies of mRNA expression profiling. Their success is due, in part, to the multiple oligonucleotide featur...
Jinwook Seo, Eric P. Hoffman
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