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» Computer-Aided Peptide Evolution for Virtual Drug Design
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GECCO
2004
Springer
15 years 4 months ago
Computer-Aided Peptide Evolution for Virtual Drug Design
Ignasi Belda, Xavier Llorà, Marc Martinell,...
BMCBI
2007
113views more  BMCBI 2007»
14 years 11 months ago
In silico panning for a non-competitive peptide inhibitor
Background: Peptide ligands have tremendous therapeutic potential as efficacious drugs. Currently, more than 40 peptides are available in the market for a drug. However, since cos...
Yukiko Yagi, Kotaro Terada, Takahisa Noma, Kazunor...
CCE
2011
14 years 5 months ago
Computational energy-based redesign of robust proteins
The robustness of a system is a property that pervades all aspects of Nature. The ability of a system to adapt itself to perturbations due to internal and external agents, to agin...
Giovanni Stracquadanio, Giuseppe Nicosia
BMCBI
2010
151views more  BMCBI 2010»
14 years 11 months ago
Using diffusion distances for flexible molecular shape comparison
Background: Many molecules are flexible and undergo significant shape deformation as part of their function, and yet most existing molecular shape comparison (MSC) methods treat t...
Yu-Shen Liu, Qi Li, Guo-Qin Zheng, Karthik Ramani,...