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135
Voted
BMCBI
2010
15 years 3 months ago
2010
Background: Principal component analysis (PCA) has gained popularity as a method for the analysis of highdimensional genomic data. However, it is often difficult to interpret the ...
139
Voted
BMCBI
2010
15 years 3 months ago
2010
Background: Random forests (RF) have been increasingly used in applications such as genome-wide association and microarray studies where predictor correlation is frequently observ...
119
Voted
BMCBI
2010
15 years 3 months ago
2010
Background: It has been long well known that genes do not act alone; rather groups of genes act in consort during a biological process. Consequently, the expression levels of gene...
163
Voted
BMCBI
2010
15 years 3 months ago
2010
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
114
Voted
BMCBI
2010
15 years 3 months ago
2010
Background: In recent years, gene order data has attracted increasing attention from both biologists and computer scientists as a new type of data for phylogenetic analysis. If ge...