Background: In order to maintain the most comprehensive structural annotation databases we must carry out regular updates for each proteome using the latest profile-profile fold r...
Liam J. McGuffin, Richard T. Smith, Kevin Bryson, ...
Background: With the advent of high-throughput proteomic experiments such as arrays of purified proteins comes the need to analyse sets of proteins as an ensemble, as opposed to t...
Background: Genome annotation can be viewed as an incremental, cooperative, data-driven, knowledge-based process that involves multiple methods to predict gene locations and struc...
Background: The accomplishment of the various genome sequencing projects resulted in accumulation of massive amount of gene sequence information. This calls for a large-scale comp...
Given a smooth surface, a blue (red) ridge is a curve such that at each of its points, the maximum (minimum) principal curvature has an extremum along its curvature line. Ridges a...