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128
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BMCBI
2004
96views more  BMCBI 2004»
15 years 17 days ago
Identification of regions in multiple sequence alignments thermodynamically suitable for targeting by consensus oligonucleotides
Background: Computer programs for the generation of multiple sequence alignments such as "Clustal W" allow detection of regions that are most conserved among many sequen...
Olga V. Matveeva, Brian T. Foley, Vladimir A. Nemt...
BMCBI
2004
113views more  BMCBI 2004»
15 years 17 days ago
Oligo kernels for datamining on biological sequences: a case study on prokaryotic translation initiation sites
Background: Kernel-based learning algorithms are among the most advanced machine learning methods and have been successfully applied to a variety of sequence classification tasks ...
Peter Meinicke, Maike Tech, Burkhard Morgenstern, ...
139
Voted
BMCBI
2004
110views more  BMCBI 2004»
15 years 17 days ago
Tools for loading MEDLINE into a local relational database
Background: Researchers who use MEDLINE for text mining, information extraction, or natural language processing may benefit from having a copy of MEDLINE that they can manage loca...
Diane E. Oliver, Gaurav Bhalotia, Ariel S. Schwart...
BMCBI
2004
123views more  BMCBI 2004»
15 years 17 days ago
A two-way interface between limited Systems Biology Markup Language and R
Background: Systems Biology Markup Language (SBML) is gaining broad usage as a standard for representing dynamical systems as data structures. The open source statistical programm...
Tomas Radivoyevitch
BMCBI
2004
151views more  BMCBI 2004»
15 years 17 days ago
Design, implementation and evaluation of a practical pseudoknot folding algorithm based on thermodynamics
Background: The general problem of RNA secondary structure prediction under the widely used thermodynamic model is known to be NP-complete when the structures considered include a...
Jens Reeder, Robert Giegerich
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