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BMCBI
2010
148views more  BMCBI 2010»
15 years 4 months ago
Calling SNPs without a reference sequence
Background: The most common application for the next-generation sequencing technologies is resequencing, where short reads from the genome of an individual are aligned to a refere...
Aakrosh Ratan, Yu Zhang, Vanessa M. Hayes, Stephan...
BMCBI
2010
86views more  BMCBI 2010»
15 years 4 months ago
Fast motif recognition via application of statistical thresholds
Background: Improving the accuracy and efficiency of motif recognition is an important computational challenge that has application to detecting transcription factor binding sites...
Christina Boucher, James King
BMCBI
2010
151views more  BMCBI 2010»
15 years 4 months ago
Using diffusion distances for flexible molecular shape comparison
Background: Many molecules are flexible and undergo significant shape deformation as part of their function, and yet most existing molecular shape comparison (MSC) methods treat t...
Yu-Shen Liu, Qi Li, Guo-Qin Zheng, Karthik Ramani,...
CORR
2008
Springer
92views Education» more  CORR 2008»
15 years 4 months ago
Accelerating Large-scale Data Exploration through Data Diffusion
Data-intensive applications often require exploratory analysis of large datasets. If analysis is performed on distributed resources, data locality can be crucial to high throughpu...
Ioan Raicu, Yong Zhao, Ian T. Foster, Alexander S....
EM
2010
155views Management» more  EM 2010»
15 years 4 months ago
Hyperbolic Graphs of Small Complexity
In this paper we enumerate and classify the "simplest" pairs (M, G) where M is a closed orientable 3-manifold and G is a trivalent graph embedded in M. To enumerate the p...
Damian Heard, Craig Hodgson, Bruno Martelli, Carlo...