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132
Voted
RECOMB
2008
Springer
16 years 3 months ago
Algorithms for Joint Optimization of Stability and Diversity in Planning Combinatorial Libraries of Chimeric Proteins
Abstract. In engineering protein variants by constructing and screening combinatorial libraries of chimeric proteins, two complementary and competing goals are desired: the new pro...
Wei Zheng, Alan M. Friedman, Chris Bailey-Kellogg
131
Voted
RECOMB
2007
Springer
16 years 3 months ago
A Bayesian Model That Links Microarray mRNA Measurements to Mass Spectrometry Protein Measurements
Abstract. An important problem in biology is to understand correspondences between mRNA microarray levels and mass spectrometry peptide counts. Recently, a compendium of mRNA expre...
Anitha Kannan, Andrew Emili, Brendan J. Frey
141
Voted
RECOMB
2005
Springer
16 years 3 months ago
Comparative Systems Biology of the Sporulation Initiation Network in Prokaryotes
Many years of experimental and computational molecular biology of model organisms such as Escherichia coli and Saccharomyces cerevisiae has elucidated the gene regulatory network i...
Michiel J. L. de Hoon, Dennis Vitkup
161
Voted
RECOMB
2005
Springer
16 years 3 months ago
An Interaction-Dependent Model for Transcription Factor Binding
Transcriptional regulation is accomplished by several transcription factor proteins that bind to specific DNA elements in the relative vicinity of the gene, and interact with each ...
Li-San Wang, Shane T. Jensen, Sridhar Hannenhalli
126
Voted
ICDE
2010
IEEE
568views Database» more  ICDE 2010»
16 years 3 months ago
Reverse Top-k Queries
Rank-aware query processing has become essential for many applications that return to the user only the top-k objects based on the individual user's preferences. Top-k queries...
Akrivi Vlachou, Christos Doulkeridis, Kjetil N&osl...