Understanding the protein folding mechanism remains a grand challenge in structural biology. In the past several years, computational theories in molecular dynamics have been empl...
Background: To further understand the implementation of hyperparameters re-estimation technique in Bayesian hierarchical model, we added two more prior assumptions over the weight...
Background: A mathematical model to understand, predict, control, or even design a real biological system is a central theme in systems biology. A dynamic biological system is alw...
In many scientific domains, researchers are turning to large-scale behavioral simulations to better understand real-world phenomena. While there has been a great deal of work on s...
Guozhang Wang, Marcos Antonio Vaz Salles, Benjamin...
Background: The modeling of dynamic systems requires estimating kinetic parameters from experimentally measured time-courses. Conventional global optimization methods used for par...