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BIB
2010
129views more  BIB 2010»
14 years 9 months ago
Pathway Tools version 13.0: integrated software for pathway/genome informatics and systems biology
PathwayTools is a production-quality software environment for creating a type of model-organism database called a Pathway/Genome Database (PGDB). A PGDB such as EcoCyc integrates ...
Peter D. Karp, Suzanne M. Paley, Markus Krummenack...
BIOINFORMATICS
2010
138views more  BIOINFORMATICS 2010»
14 years 9 months ago
Robust unmixing of tumor states in array comparative genomic hybridization data
Motivation: Tumorigenesis is an evolutionary process by which tumor cells acquire sequences of mutations leading to increased growth, invasiveness, and eventually metastasis. It i...
David Tolliver, Charalampos E. Tsourakakis, Ayshwa...
BMCBI
2010
190views more  BMCBI 2010»
14 years 9 months ago
APIS: accurate prediction of hot spots in protein interfaces by combining protrusion index with solvent accessibility
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
Jun-Feng Xia, Xing-Ming Zhao, Jiangning Song, De-S...
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BMCBI
2010
156views more  BMCBI 2010»
14 years 9 months ago
Global screening of potential Candida albicans biofilm-related transcription factors via network comparison
Background: Candida albicans is a commonly encountered fungal pathogen in humans. The formation of biofilm is a major virulence factor in C. albicans pathogenesis and is related t...
Yu-Chao Wang, Chung-Yu Lan, Wen-Ping Hsieh, Luis A...
BMCBI
2010
154views more  BMCBI 2010»
14 years 9 months ago
Binary image representation of a ligand binding site: its application to efficient sampling of a conformational ensemble
Background: Modelling the ligand binding site of a protein is an important component of understanding proteinligand interactions and is being actively studied. Even if the side ch...
Edon Sung, Sangsoo Kim, Whanchul Shin