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BMCBI
2010
104views more  BMCBI 2010»
14 years 9 months ago
Formal reasoning on qualitative models of coinfection of HIV and Tuberculosis and HAART therapy
Background: Several diseases, many of which nowadays pandemic, consist of multifactorial pathologies. Paradigmatic examples come from the immune response to pathogens, in which ca...
Anil Sorathiya, Andrea Bracciali, Pietro Liò...
BMCBI
2010
104views more  BMCBI 2010»
14 years 9 months ago
Bidirectional best hit r-window gene clusters
Background: Conserved gene clusters are groups of genes that are located close to one another in the genomes of several species. They tend to code for proteins that have a functio...
Melvin Zhang, Hon Wai Leong
BMCBI
2010
134views more  BMCBI 2010»
14 years 9 months ago
BayesMotif: de novo protein sorting motif discovery from impure datasets
Background: Protein sorting is the process that newly synthesized proteins are transported to their target locations within or outside of the cell. This process is precisely regul...
Jianjun Hu, Fan Zhang
BMCBI
2010
110views more  BMCBI 2010»
14 years 9 months ago
MultiRTA: A simple yet reliable method for predicting peptide binding affinities for multiple class II MHC allotypes
Background: The binding of peptide fragments of antigens to class II MHC is a crucial step in initiating a helper T cell immune response. The identification of such peptide epitop...
Andrew J. Bordner, Hans D. Mittelmann
BMCBI
2007
109views more  BMCBI 2007»
14 years 9 months ago
A domain-based approach to predict protein-protein interactions
Background: Knowing which proteins exist in a certain organism or cell type and how these proteins interact with each other are necessary for the understanding of biological proce...
Mudita Singhal, Haluk Resat