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» Computing Reachable States for Nonlinear Biological Models
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AUTOMATICA
2008
78views more  AUTOMATICA 2008»
14 years 11 months ago
A mathematical framework for the control of piecewise-affine models of gene networks
This article introduces results on the control of gene networks, in the context of piecewise-affine models. We propose an extension of this well-documented class of models, where ...
Etienne Farcot, Jean-Luc Gouzé
ENTCS
2010
118views more  ENTCS 2010»
14 years 9 months ago
Fragments-based Model Reduction: Some Case Studies
Molecular biological models usually suffer from a dramatic combinatorial blow up. Indeed, proteins form complexes and can modify each others, which leads to the formation of a hug...
Jérôme Feret
BMCBI
2006
102views more  BMCBI 2006»
14 years 11 months ago
SNA - a toolbox for the stoichiometric analysis of metabolic networks
Background: Despite recent algorithmic and conceptual progress, the stoichiometric network analysis of large metabolic models remains a computationally challenging problem. Result...
Robert Urbanczik
BIOSYSTEMS
2008
107views more  BIOSYSTEMS 2008»
14 years 11 months ago
The linearity of emergent spectro-temporal receptive fields in a model of auditory cortex
The responses of cortical neurons are often characterized by measuring their spectro-temporal receptive fields (strfs). The strf of a cell can be thought of as a representation of...
Martin Coath, Emili Balaguer-Ballester, Sue L. Den...
CEC
2010
IEEE
14 years 6 months ago
Parameter estimation with term-wise decomposition in biochemical network GMA models by hybrid regularized Least Squares-Particle
High-throughput analytical techniques such as nuclear magnetic resonance, protein kinase phosphorylation, and mass spectroscopic methods generate time dense profiles of metabolites...
Prospero C. Naval, Luis G. Sison, Eduardo R. Mendo...