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» Computing a Center-Transversal Line
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151
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BMCBI
2010
131views more  BMCBI 2010»
15 years 3 months ago
Prediction of epigenetically regulated genes in breast cancer cell lines
Background: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation o...
Leandro A. Loss, Anguraj Sadanandam, Steffen Durin...
133
Voted
BMCBI
2010
84views more  BMCBI 2010»
15 years 3 months ago
An integrated analysis of molecular aberrations in NCI-60 cell lines
Background: Cancer is a complex disease where various types of molecular aberrations drive the development and progression of malignancies. Large-scale screenings of multiple type...
Chen-Hsiang Yeang
BMCBI
2007
154views more  BMCBI 2007»
15 years 3 months ago
Bounds on the distribution of the number of gaps when circles and lines are covered by fragments: Theory and practical applicati
Background: The question of how a circle or line segment becomes covered when random arcs are marked off has arisen repeatedly in bioinformatics. The number of uncovered gaps is o...
John Moriarty, Julian R. Marchesi, Anthony Metcalf...
141
Voted
BMCBI
2010
133views more  BMCBI 2010»
15 years 3 months ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang
160
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CN
2004
256views more  CN 2004»
15 years 3 months ago
A line in the sand: a wireless sensor network for target detection, classification, and tracking
Intrusion detection is a surveillance problem of practical import that is well suited to wireless sensor networks. In this paper, we study the application of sensor networks to the...
Anish Arora, Prabal Dutta, Sandip Bapat, Vinod Kul...