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ARTMED
2006
80views more  ARTMED 2006»
14 years 10 months ago
A formal theory for spatial representation and reasoning in biomedical ontologies
Objective: The objective of this paper is to demonstrate how a formal spatial theory can be used as an important tool for disambiguating the spatial information embodied in biomed...
Maureen Donnelly, Thomas Bittner, Cornelius Rosse
BMCBI
2006
119views more  BMCBI 2006»
14 years 10 months ago
Utilization of two sample t-test statistics from redundant probe sets to evaluate different probe set algorithms in GeneChip stu
Background: The choice of probe set algorithms for expression summary in a GeneChip study has a great impact on subsequent gene expression data analysis. Spiked-in cRNAs with know...
Zihua Hu, Gail R. Willsky
BMCBI
2006
115views more  BMCBI 2006»
14 years 10 months ago
SimArray: a user-friendly and user-configurable microarray design tool
Background: Microarrays were first developed to assess gene expression but are now also used to map protein-binding sites and to assess allelic variation between individuals. Rega...
Richard P. Auburn, Roslin R. Russell, Bettina Fisc...
BMCBI
2006
112views more  BMCBI 2006»
14 years 10 months ago
Algorithms for incorporating prior topological information in HMMs: application to transmembrane proteins
Background: Hidden Markov Models (HMMs) have been extensively used in computational molecular biology, for modelling protein and nucleic acid sequences. In many applications, such...
Pantelis G. Bagos, Theodore D. Liakopoulos, Stavro...
BMCBI
2006
98views more  BMCBI 2006»
14 years 10 months ago
JLIN: A java based linkage disequilibrium plotter
Background: A great deal of effort and expense are being expended internationally in attempts to detect genetic polymorphisms contributing to susceptibility to complex human disea...
Kim W. Carter, Pamela A. McCaskie, Lyle J. Palmer
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