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138
Voted
RECOMB
2005
Springer
16 years 4 months ago
2005
Springer
Abstract. Asymmetric functional divergence of paralogues is a key aspect of the traditional model of evolution following duplication. If one gene continues to perform the ancestral...
112
Voted
RECOMB
2004
Springer
16 years 4 months ago
2004
Springer
Identifying gene clusters, genomic regions that share local similarities in gene organization, is a prerequisite for many different types of genomic analyses, including operon pred...
136
Voted
RECOMB
2003
Springer
16 years 4 months ago
2003
Springer
We develop a new framework for inferring models of transcriptional regulation. The models in this approach, which we call physical models, are constructed on the basis of verifiab...
125
Voted
RECOMB
2002
Springer
16 years 4 months ago
2002
Springer
We present algorithms for time-series gene expression analysis that permit the principled estimation of unobserved timepoints, clustering, and dataset alignment. Each expression p...
194
Voted
RECOMB
2001
Springer
16 years 4 months ago
2001
Springer
motif discovery problem abstracts the task of discovering short, conserved sites in genomic DNA. Pevzner and Sze recently described a precise combinatorial formulation of motif di...