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ALIFE
2005
14 years 11 months ago
Transient Phenomena in Learning and Evolution: Genetic Assimilation and Genetic Redistribution
Deacon has recently proposed that complexes of genes can be integrated into functional groups as a result of environmental changes that mask and unmask selection pressures. For exa...
Janet Wiles, James Watson, Bradley Tonkes, Terrenc...
BMCBI
2005
161views more  BMCBI 2005»
14 years 11 months ago
Non-linear mapping for exploratory data analysis in functional genomics
Background: Several supervised and unsupervised learning tools are available to classify functional genomics data. However, relatively less attention has been given to exploratory...
Francisco Azuaje, Haiying Wang, Alban Chesneau
BMCBI
2005
126views more  BMCBI 2005»
14 years 11 months ago
Integrative analysis of multiple gene expression profiles with quality-adjusted effect size models
Background: With the explosion of microarray studies, an enormous amount of data is being produced. Systematic integration of gene expression data from different sources increases...
Pingzhao Hu, Celia M. T. Greenwood, Joseph Beyene
BMCBI
2005
94views more  BMCBI 2005»
14 years 11 months ago
Measuring similarities between transcription factor binding sites
Background: Collections of transcription factor binding profiles (Transfac, Jaspar) are essential to identify regulatory elements in DNA sequences. Subsets of highly similar profi...
Szymon M. Kielbasa, Didier Gonze, Hanspeter Herzel
BMCBI
2005
132views more  BMCBI 2005»
14 years 11 months ago
Kalign - an accurate and fast multiple sequence alignment algorithm
Background: The alignment of multiple protein sequences is a fundamental step in the analysis of biological data. It has traditionally been applied to analyzing protein families f...
Timo Lassmann, Erik L. L. Sonnhammer