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CBMS
2008
IEEE
15 years 2 months ago
Generating GO Slim Using Relational Database Management Systems to Support Proteomics Analysis
The Gene Ontology Consortium built the Gene Ontology database (GO) to address the need for a common standard in naming genes and gene products. Using different names for the same ...
Getiria Onsongo, Hongwei Xie, Timothy J. Griffin, ...
95
Voted
BMCBI
2010
120views more  BMCBI 2010»
15 years 22 days ago
Short clones or long clones? A simulation study on the use of paired reads in metagenomics
Background: Metagenomics is the study of environmental samples using sequencing. Rapid advances in sequencing technology are fueling a vast increase in the number and scope of met...
Suparna Mitra, Max Schubach, Daniel H. Huson
123
Voted
BMCBI
2005
106views more  BMCBI 2005»
15 years 15 days ago
SIMPROT: Using an empirically determined indel distribution in simulations of protein evolution
Background: General protein evolution models help determine the baseline expectations for the evolution of sequences, and they have been extensively useful in sequence analysis an...
Andy Pang, Andrew D. Smith, Paulo A. S. Nuin, Elis...
BMCBI
2006
160views more  BMCBI 2006»
15 years 20 days ago
Gene prediction in eukaryotes with a generalized hidden Markov model that uses hints from external sources
Background: In order to improve gene prediction, extrinsic evidence on the gene structure can be collected from various sources of information such as genome-genome comparisons an...
Mario Stanke, Oliver Schöffmann, Burkhard Mor...
BMCBI
2002
126views more  BMCBI 2002»
15 years 13 days ago
RIO: Analyzing proteomes by automated phylogenomics using resampled inference of orthologs
Background: When analyzing protein sequences using sequence similarity searches, orthologous sequences (that diverged by speciation) are more reliable predictors of a new protein&...
Christian M. Zmasek, Sean R. Eddy