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BMCBI
2010
167views more  BMCBI 2010»
15 years 6 months ago
Creating PWMs of transcription factors using 3D structure-based computation of protein-DNA free binding energies
Background: Knowledge of transcription factor-DNA binding patterns is crucial for understanding gene transcription. Numerous DNA-binding proteins are annotated as transcription fa...
Denitsa Alamanova, Philip Stegmaier, Alexander E. ...
CMSB
2009
Springer
16 years 25 days ago
The Equivalence between Biology and Computation
A major challenge in computational systems biology is the articulation of a biological process in a form which can be understood by the biologist yet is amenable to computational e...
John K. Heath
BIOSURVEILLANCE
2007
Springer
16 years 13 days ago
High Performance Computing for Disease Surveillance
Abstract. The global health, threatened by emerging infectious diseases, pandemic influenza, and biological warfare, is becoming increasingly dependent on the rapid acquisition, p...
David W. Bauer, Brandon W. Higgs, Mojdeh Mohtashem...
PPAM
2005
Springer
15 years 11 months ago
SILC: A Flexible and Environment-Independent Interface for Matrix Computation Libraries
We propose a new framework, named Simple Interface for Library Collections (SILC), that gives users access to matrix computation libraries in a flexible and environment-independen...
Tamito Kajiyama, Akira Nukada, Hidehiko Hasegawa, ...
IPPS
1999
IEEE
15 years 10 months ago
DEFACTO: A Design Environment for Adaptive Computing Technology
The lack of high-level design tools hampers the widespread adoption of adaptive computing systems. Application developers have to master a wide range of functions, from the high-le...
Kiran Bondalapati, Pedro C. Diniz, Phillip Duncan,...