Background: During meiosis, homologous chromosomes exchange segments via the formation of crossovers. This phenomenon is highly regulated; in particular, crossovers are distribute...
Franck Gauthier, Olivier C. Martin, Matthieu Falqu...
Background: Molecular database search tools need statistical models to assess the significance for the resulting hits. In the classical approach one asks the question how probable...
Stefan Wolfsheimer, Inke Herms, Sven Rahmann, Alex...
Abstract. Gene trees are leaf-labeled trees inferred from molecular sequences. Due to duplication events arising in genome evolution, gene trees usually have multiple copies of som...
Abstract--We propose a framework for the nonlinear spatiotemporal registration of 4D time-series of images based on the Diffeomorphic Demons (DD) algorithm. In this framework, the ...
Jean-Marc Peyrat, Herve Delingette, Maxime Sermesa...
Background: Using microarray and sequencing platforms, a large number of copy number variations (CNVs) have been identified in humans. In practice, because our human genome is a d...