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BIOINFORMATICS
2005
140views more  BIOINFORMATICS 2005»
14 years 9 months ago
Profile-based direct kernels for remote homology detection and fold recognition
Motivation: Remote homology detection between protein sequences is a central problem in computational biology. Supervised learning algorithms based on support vector machines are ...
Huzefa Rangwala, George Karypis
76
Voted
RECOMB
2006
Springer
15 years 10 months ago
Domain Architecture in Homolog Identification
Homology identification is the first step for many genomic studies. Current methods, based on sequence comparison, can result in a substantial number of mis-assignments due to the ...
Nan Song, R. D. Sedgewick, Dannie Durand
CIBCB
2006
IEEE
15 years 3 months ago
Aggregating Homologous Protein Families in Evolutionary Reconstructions of Herpesviruses
Abstract–Protein families can be used to reconstruct evolutionary histories of organisms. The accuracy of protein assignment to such families is critical for the success of such ...
Boris Mirkin, Renata da Silva Camargo, Trevor I. F...
ICASSP
2011
IEEE
14 years 1 months ago
Iterative estimation of structures of multiple RNA homologs: Turbofold
TurboFold, an iterative algorithm for estimating the common secondary structures of multiple RNA homologs, is presented. The algorithm is motivated by and has structure and attrib...
Gaurav Sharma, Arif Ozgun Harmanci, David H. Mathe...
CSB
2003
IEEE
176views Bioinformatics» more  CSB 2003»
15 years 2 months ago
3D Structural Homology Detection via Unassigned Residual Dipolar Couplings
Recognition of a protein’s fold provides valuable information about its function. While many sequence-based homology prediction methods exist, an important challenge remains: tw...
Christopher James Langmead, Bruce Randall Donald