729 search results - page 62 / 146 » Computing persistent homology |
BMCBI
2008
14 years 10 months ago
2008
Background: Protein structure prediction methods provide accurate results when a homologous protein is predicted, while poorer predictions are obtained in the absence of homologou...
BMCBI
2006
14 years 9 months ago
2006
Sequence homologs are an important source of information about proteins. Amino acid profiles, representing the position-specific mutation probabilities found in profiles, are a ri...
BMCBI
2005
14 years 9 months ago
2005
Background: The inference of homology from statistically significant sequence similarity is a central issue in sequence alignments. So far the statistical distribution function un...
BMCBI
2004
14 years 9 months ago
2004
Background: The increasing number of protein sequences and 3D structure obtained from genomic initiatives is leading many of us to focus on proteomics, and to dedicate our experim...
BMCBI
2004
14 years 9 months ago
2004
Background: Profile-based analysis of multiple sequence alignments (MSA) allows for accurate comparison of protein families. Here, we address the problems of detecting statistical...