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BMCBI
2008
143views more  BMCBI 2008»
14 years 10 months ago
Gene identification and protein classification in microbial metagenomic sequence data via incremental clustering
Background: The identification and study of proteins from metagenomic datasets can shed light on the roles and interactions of the source organisms in their communities. However, ...
Shibu Yooseph, Weizhong Li, Granger G. Sutton
BMCBI
2008
95views more  BMCBI 2008»
14 years 10 months ago
PURE: A webserver for the prediction of domains in unassigned regions in proteins
Background: Protein domains are the structural and functional units of proteins. The ability to parse proteins into different domains is important for effective classification, un...
Chilamakuri C. S. Reddy, Khader Shameer, Bernard O...
TC
2010
14 years 8 months ago
Network-on-Chip Hardware Accelerators for Biological Sequence Alignment
—The most pervasive compute operation carried out in almost all bioinformatics applications is pairwise sequence homology detection (or sequence alignment). Due to exponentially ...
Souradip Sarkar, Gaurav Ramesh Kulkarni, Partha Pr...
RECOMB
2009
Springer
15 years 4 months ago
Protein Fragment Swapping: A Method for Asymmetric, Selective Site-Directed Recombination
This paper presents a new approach to site-directed recombination, swapping combinations of selected discontiguous fragments from a source protein in place of corresponding fragmen...
Wei Zheng, Karl E. Griswold, Chris Bailey-Kellogg
ECCB
2008
IEEE
15 years 4 months ago
Connect the dots: exposing hidden protein family connections from the entire sequence tree
Motivation: Mapping of remote evolutionary links is a classic computational problem of much interest. Relating protein families allows for functional and structural inference on u...
Yaniv Loewenstein, Michal Linial