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BMCBI
2010
190views more  BMCBI 2010»
14 years 12 months ago
A parallel and incremental algorithm for efficient unique signature discovery on DNA databases
Background: DNA signatures are distinct short nucleotide sequences that provide valuable information that is used for various purposes, such as the design of Polymerase Chain Reac...
Hsiao Ping Lee, Tzu-Fang Sheu, Chuan Yi Tang
BMCBI
2010
193views more  BMCBI 2010»
14 years 12 months ago
Probe set filtering increases correlation between Affymetrix GeneChip and qRT-PCR expression measurements
Background: Affymetrix GeneChip microarrays are popular platforms for expression profiling in two types of studies: detection of differential expression computed by p-values of t-...
Jakub Mieczkowski, Magdalena E. Tyburczy, Michal D...
BMCBI
2010
176views more  BMCBI 2010»
14 years 12 months ago
TargetSpy: a supervised machine learning approach for microRNA target prediction
Background: Virtually all currently available microRNA target site prediction algorithms require the presence of a (conserved) seed match to the 5' end of the microRNA. Recen...
Martin Sturm, Michael Hackenberg, David Langenberg...
BMCBI
2010
86views more  BMCBI 2010»
14 years 12 months ago
An automatic method for identifying surface proteins in bacteria: SLEP
Background: Bacterial infections represent a global health challenge. The identification of novel antibacterial targets for both therapy and vaccination is needed on a constant ba...
Emanuela Giombini, Massimiliano Orsini, Danilo Car...
BMCBI
2010
102views more  BMCBI 2010»
14 years 12 months ago
Missing genes in the annotation of prokaryotic genomes
Background: Protein-coding gene detection in prokaryotic genomes is considered a much simpler problem than in intron-containing eukaryotic genomes. However there have been reports...
Andrew S. Warren, Jeremy S. Archuleta, Wu-chun Fen...
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