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83
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BMCBI
2007
14 years 9 months ago
2007
Background: Despite a remarkable success in the computational prediction of genes in Bacteria and Archaea, a lack of comprehensive understanding of prokaryotic gene structures pre...
79
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BMCBI
2007
14 years 9 months ago
2007
Background: Structural genomics initiatives are producing increasing numbers of threedimensional (3D) structures for which there is little functional information. Structure-based ...
106
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BMCBI
2007
14 years 9 months ago
2007
Background: Much recent work in bioinformatics has focused on the inference of various types of biological networks, representing gene regulation, metabolic processes, protein-pro...
BMCBI
2007
14 years 9 months ago
2007
Background: Staphylococcus aureus is a human pathogen that causes a wide variety of lifethreatening infections using a large number of virulence factors. One of the major global r...
BMCBI
2007
14 years 9 months ago
2007
Background: When proteins are subjected to proteolytic digestion and analyzed by mass spectrometry using a method such as 2D LC MS/MS, only a portion of the proteotypic peptides a...