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» Computing with Evolving Proteins
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RECOMB
2006
Springer
15 years 10 months ago
De Novo Signaling Pathway Predictions Based on Protein-Protein Interaction, Targeted Therapy and Protein Microarray Analysis
Abstract. Mapping intra-cellular signaling networks is a critical step in developing an understanding of and treatments for many devastating diseases. The predominant ways of disco...
Derek A. Ruths, Jen-Te Tseng, Luay Nakhleh, Prahla...
NAR
2007
100views more  NAR 2007»
14 years 9 months ago
PIC: Protein Interactions Calculator
Interactions within a protein structure and interactions between proteins in an assembly are essential considerations in understanding molecular basis of stability and functions o...
K. G. Tina, R. Bhadra, N. Srinivasan
BMCBI
2010
205views more  BMCBI 2010»
14 years 9 months ago
A fast indexing approach for protein structure comparison
Background: Protein structure comparison is a fundamental task in structural biology. While the number of known protein structures has grown rapidly over the last decade, searchin...
Lei Zhang, James Bailey, Arun Siddharth Konagurthu...
BMCBI
2006
150views more  BMCBI 2006»
14 years 9 months ago
Protein structure similarity from principle component correlation analysis
Background: Owing to rapid expansion of protein structure databases in recent years, methods of structure comparison are becoming increasingly effective and important in revealing...
Xiaobo Zhou, James Chou, Stephen T. C. Wong
ISMB
2000
14 years 11 months ago
Towards a Systematics for Protein Subcellular Location: Quantitative Description of Protein Localization Patterns and Automated
Determination of the functions of all expressed proteins represents one of the major upcoming challenges in computational molecular biology. Since subcellular location plays a cru...
Robert F. Murphy, Michael V. Boland, Meel Velliste