Discrete motifsthat discriminate functionalclasses of proteins are useful for classifying newsequences, capturingstructural constraints, andidentifyingprotein subclasses.Despiteth...
Craig G. Nevill-Manning, Komal S. Sethi, Thomas D....
The process by which a cell senses and responds to its environment, as in signal transduction, is often mediated by a network of protein-protein interactions, in which proteins co...
James R. Faeder, Michael L. Blinov, William S. Hla...
Structural biology research places significant demands upon computing and informatics infrastructure. Protein production, crystallization and X-ray data collection require solutio...
Noel G. Faux, Anthony Beitz, Mark A. Bate, Abdulla...
This paper describes a parallel FPGA implementation of a genomic sequence comparison algorithm for finding similarities between a large set of protein sequences and full genomes....
Van Hoa Nguyen, Alexandre Cornu, Dominique Lavenie...
Molecular interaction databases can be used to study the evolution of molecular pathways across species. Querying such pathways is a challenging computational problem, and recent e...