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» Computing with Evolving Proteins
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ICDM
2005
IEEE
125views Data Mining» more  ICDM 2005»
15 years 3 months ago
Alternate Representation of Distance Matrices for Characterization of Protein Structure
The most suitable method for the automated classification of protein structures remains an open problem in computational biology. In order to classify a protein structure with an...
Keith Marsolo, Srinivasan Parthasarathy
CPM
2006
Springer
125views Combinatorics» more  CPM 2006»
15 years 1 months ago
Geometric Suffix Tree: A New Index Structure for Protein 3-D Structures
Abstract. Protein structure analysis is one of the most important research issues in the post-genomic era, and faster and more accurate query data structures for such 3-D structure...
Tetsuo Shibuya
BMCBI
2010
190views more  BMCBI 2010»
14 years 10 months ago
APIS: accurate prediction of hot spots in protein interfaces by combining protrusion index with solvent accessibility
Background: It is well known that most of the binding free energy of protein interaction is contributed by a few key hot spot residues. These residues are crucial for understandin...
Jun-Feng Xia, Xing-Ming Zhao, Jiangning Song, De-S...
BMCBI
2007
129views more  BMCBI 2007»
14 years 10 months ago
Exploring inconsistencies in genome-wide protein function annotations: a machine learning approach
Background: Incorrectly annotated sequence data are becoming more commonplace as databases increasingly rely on automated techniques for annotation. Hence, there is an urgent need...
Carson M. Andorf, Drena Dobbs, Vasant Honavar
BMCBI
2006
98views more  BMCBI 2006»
14 years 10 months ago
Optimised amino acid specific weighting factors for unbound protein docking
Background: One of the most challenging aspects of protein-protein docking is the inclusion of flexibility into the docking procedure. We developed a postfilter where the grid-rep...
Philipp Heuser, Dietmar Schomburg