The directed evolution of proteins, using an in vitro domainal shuffling strategy was proposed in (J. Kolkman and W. Stemmer, Nat. Biotech. 19, 423 (2001). Due to backhybridization...
John A. Rose, Russell J. Deaton, Masami Hagiya, Ak...
Background: Metal-containing proteins comprise a diverse and sizable category within the proteomes of organisms, ranging from proteins that use metals to catalyze reactions to pro...
W. Andrew Lancaster, Jeremy L. Praissman, Farris L...
Protein data contain discriminative patterns that can be used in many beneficial applications if they are defined correctly. In this work sequential pattern mining (SPM) is utiliz...
Themis P. Exarchos, Costas Papaloukas, Christos La...
We develop an integrated probabilistic model to combine protein physical interactions, genetic interactions, highly correlated gene expression network, protein complex data, and d...
Background: Since experimental determination of protein folding pathways remains difficult, computational techniques are often used to simulate protein folding. Most current techn...