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» Computing with Evolving Proteins
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DNA
2001
Springer
125views Bioinformatics» more  DNA 2001»
15 years 2 months ago
PNA-mediated Whiplash PCR
The directed evolution of proteins, using an in vitro domainal shuffling strategy was proposed in (J. Kolkman and W. Stemmer, Nat. Biotech. 19, 423 (2001). Due to backhybridization...
John A. Rose, Russell J. Deaton, Masami Hagiya, Ak...
BMCBI
2011
14 years 4 months ago
A Computational Framework for Proteome-Wide Pursuit and Prediction of Metalloproteins using ICP-MS and MS/MS Data
Background: Metal-containing proteins comprise a diverse and sizable category within the proteomes of organisms, ranging from proteins that use metals to catalyze reactions to pro...
W. Andrew Lancaster, Jeremy L. Praissman, Farris L...
JBI
2008
137views Bioinformatics» more  JBI 2008»
14 years 9 months ago
Mining sequential patterns for protein fold recognition
Protein data contain discriminative patterns that can be used in many beneficial applications if they are defined correctly. In this work sequential pattern mining (SPM) is utiliz...
Themis P. Exarchos, Costas Papaloukas, Christos La...
RECOMB
2003
Springer
15 years 10 months ago
An integrated probabilistic model for functional prediction of proteins
We develop an integrated probabilistic model to combine protein physical interactions, genetic interactions, highly correlated gene expression network, protein complex data, and d...
Minghua Deng, Ting Chen, Fengzhu Sun
BMCBI
2008
168views more  BMCBI 2008»
14 years 9 months ago
Predicting protein folding pathways at the mesoscopic level based on native interactions between secondary structure elements
Background: Since experimental determination of protein folding pathways remains difficult, computational techniques are often used to simulate protein folding. Most current techn...
Qingwu Yang, Sing-Hoi Sze