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» Computing with Evolving Proteins
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RECOMB
2006
Springer
15 years 10 months ago
CONTRAlign: Discriminative Training for Protein Sequence Alignment
In this paper, we present CONTRAlign, an extensible and fully automatic framework for parameter learning and protein pairwise sequence alignment using pair conditional random field...
Chuong B. Do, Samuel S. Gross, Serafim Batzoglou
CIBCB
2007
IEEE
15 years 4 months ago
A Comparison of Sequence Kernels for Localization Prediction of Transmembrane Proteins
Abstract— We applied Support Vector Machines to the prediction of the subcellular localization of transmembrane proteins, and compared the performance of different sequence kerne...
Stefan Maetschke, Marcus Gallagher, Mikael Bod&eac...
GECCO
2007
Springer
154views Optimization» more  GECCO 2007»
15 years 4 months ago
A novel ab-initio genetic-based approach for protein folding prediction
In this paper, a model based on genetic algorithms for protein folding prediction is proposed. The most important features of the proposed approach are: i) Heuristic secondary str...
Sergio Raul Duarte Torres, David Camilo Becerra Ro...
RECOMB
2005
Springer
15 years 3 months ago
Probabilistic in Silico Prediction of Protein-Peptide Interactions
Abstract. Peptide recognition modules (PRMs) are specialised compact protein domains that mediate many important protein-protein interactions. They are responsible for the assembly...
Wolfgang P. Lehrach, Dirk Husmeier, Christopher K....
ISMB
1998
14 years 11 months ago
Modeling Protein Homopolymeric Repeats: Possible Polyglutamine Structural Motifs for Huntington's Disease
Wedescribe a prototype system (Poly-X) for assisting an expert user in modelingprotein repeats. Poly-X reduces the large numberof degrees of freedomrequired to specify a protein m...
Richard H. Lathrop, Malcolm S. Casale, Douglas J. ...