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» Computing with Evolving Proteins
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ICASSP
2007
IEEE
15 years 5 months ago
Evolutionary Sequence Modeling for Discovery of Peptide Hormones
There are currently a large number of ‘‘orphan’’ G-protein-coupled receptors (GPCRs) whose endogenous ligands (peptide hormones) are unknown. Identification of these pepti...
M. Kemal Sönmez, Lawrence Toll, Nina Zaveri
101
Voted
CSB
2005
IEEE
136views Bioinformatics» more  CSB 2005»
15 years 4 months ago
Whole Genome Phylogeny Based on Clustered Signature String Composition
Peptide compositions constructed out of whole sets of protein sequences can be used as species signatures for phylogenetic analysis. To account for point mutations, an amino acid ...
Xiaomeng Wu, Guohui Lin, Xiu-Feng Wan, Dong Xu
CSB
2004
IEEE
15 years 2 months ago
Space-Conserving Optimal DNA-Protein Alignment
DNA-protein alignment algorithms can be used to discover coding sequences in a genomic sequence, if the corresponding protein derivatives are known. They can also be used to ident...
Pang Ko, Mahesh Narayanan, Anantharaman Kalyanaram...
CCCG
2006
15 years 8 days ago
On the Maximum Span of Fixed-Angle Chains
Soss proved that it is NP-hard to find the maximum flat span of a fixed-angle polygonal chain: the largest distance achievable between the endpoints in a planar embedding. These f...
Nadia Benbernou, Joseph O'Rourke
75
Voted
JCC
2008
85views more  JCC 2008»
14 years 10 months ago
Minimal molecular surfaces and their applications
Abstract: This article presents a novel concept, the minimal molecular surface (MMS), for the theoretical modeling of biomolecules. The MMS can be viewed as a result of the surface...
P. W. Bates, G. W. Wei, Shan Zhao