—Proteins are the main players in the game of life. Good understanding of their structures, functions, and behaviors leads to good understanding of drugs, diseases, and thus our ...
Wehave recently described a method based on Artificial Neural Networksto cluster protein sequences into families. The network was trained with Kohonen’s unsupervised-learning al...
The polyglutamine diseases are caused in part by a gain-of-function mechanism of neuronal toxicity involving protein conformational changes that result in the formation and deposi...
Amy L. Robertson, Mark A. Bate, Steve G. Androulak...
Background: While occurring enzymatically in biological systems, O-linked glycosylation affects protein folding, localization and trafficking, protein solubility, antigenicity, bi...