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» Computing with Evolving Proteins
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NAR
2011
223views Computer Vision» more  NAR 2011»
14 years 16 days ago
KUPS: constructing datasets of interacting and non-interacting protein pairs with associated attributions
KUPS (The University of Kansas Proteomics Service) provides high-quality protein–protein interaction (PPI) data for researchers developing and evaluating computational models fo...
Xue-wen Chen, Jong Cheol Jeong, Patrick Dermyer
RECOMB
2002
Springer
15 years 10 months ago
A dimensionality reduction approach to modeling protein flexibility
Proteins are involved either directly or indirectly in all biological processes in living organisms. It is now widely accepted that conformational changes of proteins can critical...
Miguel L. Teodoro, George N. Phillips, Lydia E. Ka...
125
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CIBCB
2009
IEEE
14 years 10 months ago
Improved prediction of trans-membrane spans in proteins using an artificial neural network
Tools for the identification of trans-membrane spans from the protein sequence are widely used in the experimental community. Computational structural biology seeks to increase the...
Julia Koehler, Ralf Mueller, Jens Meiler
BIBM
2009
IEEE
140views Bioinformatics» more  BIBM 2009»
15 years 1 months ago
A Protein-Protein Interaction Prediction Method Embracing Intra-protein Domain Cohesion Information
Recently, many computational methods for predicting protein-protein interaction (PPI) have been developed by utilizing domain-domain interaction or associated information. However...
Woo-Hyuk Jang, Suk Hoon Jung, Bo-ra Hyun, Dong-Soo...
BMCBI
2008
102views more  BMCBI 2008»
14 years 9 months ago
Stability of the core domain of p53: insights from computer simulations
: The tumour suppressor protein p53 protein has a core domain that binds DNA and is the site for most oncogenic mutations. This domain is quite unstable compared to its homologs p...
Arumugam Madhumalar, Derek John Smith, Chandra Ver...