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» Computing with Evolving Proteins
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NAR
2008
142views more  NAR 2008»
14 years 10 months ago
CMGSDB: integrating heterogeneous Caenorhabditis elegans data sources using compositional data mining
CMGSDB (Database for Computational Modeling of Gene Silencing) is an integration of heterogeneous data sources about Caenorhabditis elegans with capabilities for compositional dat...
Amrita Pati, Ying Jin, Karsten Klage, Richard F. H...
76
Voted
JCB
2007
168views more  JCB 2007»
14 years 10 months ago
Fast Molecular Shape Matching Using Contact Maps
In this paper, we study the problem of computing the similarity of two protein structures ring their contact-map overlap. Contact-map overlap abstracts the problem of computing th...
Pankaj K. Agarwal, Nabil H. Mustafa, Yusu Wang
90
Voted
JCB
2002
131views more  JCB 2002»
14 years 10 months ago
Modeling and Simulation of Genetic Regulatory Systems: A Literature Review
In order to understand the functioning of organisms on the molecular level, we need to know which genes are expressed, when and where in the organism, and to which extent. The reg...
Hidde de Jong
68
Voted
NCA
2007
IEEE
14 years 9 months ago
A data reduction approach for resolving the imbalanced data issue in functional genomics
Learning from imbalanced data occurs frequently in many machine learning applications. One positive example to thousands of negative instances is common in scientific applications...
Kihoon Yoon, Stephen Kwek
73
Voted
JCC
2010
105views more  JCC 2010»
14 years 8 months ago
Fast determination of the optimal rotational matrix for macromolecular superpositions
: Finding the rotational matrix that minimizes the sum of squared deviations between two vectors is an important problem in bioinformatics and crystallography. Traditional algorith...
Pu Liu, Dimitris K. Agrafiotis, Douglas L. Theobal...