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» Computing with Evolving Proteins
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COMPLIFE
2005
Springer
15 years 3 months ago
MAPPIS: Multiple 3D Alignment of Protein-Protein Interfaces
A protein-protein interface (PPI) is defined by a pair of regions of two interacting protein molecules that are linked by non-covalent bonds. Recognition of conserved 3D patterns ...
Alexandra Shulman-Peleg, Maxim Shatsky, Ruth Nussi...
BMCBI
2007
131views more  BMCBI 2007»
14 years 9 months ago
On the detection of functionally coherent groups of protein domains with an extension to protein annotation
Background: Protein domains coordinate to perform multifaceted cellular functions, and domain combinations serve as the functional building blocks of the cell. The available metho...
William A. McLaughlin, Ken Chen, Tingjun Hou, Wei ...
RECOMB
2006
Springer
15 years 10 months ago
A Parameterized Algorithm for Protein Structure Alignment
This paper proposes a parameterized algorithm for aligning two protein structures, in the case where one protein structure is represented by a contact map graph and the other by a ...
Jinbo Xu, Feng Jiao, Bonnie Berger
BMCBI
2010
125views more  BMCBI 2010»
14 years 9 months ago
In-silico prediction of blood-secretory human proteins using a ranking algorithm
Background: Computational identification of blood-secretory proteins, especially proteins with differentially expressed genes in diseased tissues, can provide highly useful inform...
Qi Liu, Juan Cui, Qiang Yang, Ying Xu
BMCBI
2008
178views more  BMCBI 2008»
14 years 9 months ago
A discriminative method for protein remote homology detection and fold recognition combining Top-n-grams and latent semantic ana
Background: Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) ...
Bin Liu, Xiaolong Wang, Lei Lin, Qiwen Dong, Xuan ...