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» Computing with Evolving Proteins
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RECOMB
2006
Springer
15 years 10 months ago
Detecting MicroRNA Targets by Linking Sequence, MicroRNA and Gene Expression Data
MicroRNAs (miRNAs) have recently been discovered as an important class of non-coding RNA genes that play a major role in regulating gene expression, providing a means to control th...
Jim C. Huang, Quaid Morris, Brendan J. Frey
RECOMB
2005
Springer
15 years 10 months ago
Information Theoretic Approaches to Whole Genome Phylogenies
We describe a novel method for efficient reconstruction of phylogenetic trees, based on sequences of whole genomes or proteomes, whose lengths may greatly vary. The core of our me...
David Burstein, Igor Ulitsky, Tamir Tuller, Benny ...
IPPS
2009
IEEE
15 years 4 months ago
Accelerating HMMer on FPGAs using systolic array based architecture
HMMer is a widely-used bioinformatics software package that uses profile HMMs (Hidden Markov Models) to model the primary structure consensus of a family of protein or nucleic aci...
Yanteng Sun, Peng Li, Guochang Gu, Yuan Wen, Yuan ...
ISVC
2009
Springer
15 years 4 months ago
Wavelet-Based Representation of Biological Shapes
Modeling, characterization and analysis of biological shapes and forms are important in many computational biology studies. Shape representation challenges span the spectrum from s...
Bin Dong, Yu Mao, Ivo D. Dinov, Zhuowen Tu, Yongga...
SSDBM
2006
IEEE
163views Database» more  SSDBM 2006»
15 years 3 months ago
ACache: Using Caching to Improve the Performance of Multiple Sequence Alignments
Multiple sequence alignment represents a class of powerful bioinformatics tools with many uses in computational biology ranging from discovery of characteristic motifs and conserv...
Xun Tu, Kajal T. Claypool, Cindy X. Chen