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» Computing with Evolving Proteins
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BMCBI
2007
106views more  BMCBI 2007»
14 years 9 months ago
Constructing a meaningful evolutionary average at the phylogenetic center of mass
Background: As a consequence of the evolutionary process, data collected from related species tend to be similar. This similarity by descent can obscure subtler signals in the dat...
Eric A. Stone, Arend Sidow
BMCBI
2010
113views more  BMCBI 2010»
14 years 9 months ago
Use of historic metabolic biotransformation data as a means of anticipating metabolic sites using MetaPrint2D and Bioclipse
Background: Predicting metabolic sites is important in the drug discovery process to aid in rapid compound optimisation. No interactive tool exists and most of the useful tools ar...
Lars Carlsson, Ola Spjuth, Samuel Adams, Robert C....
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BMCBI
2007
146views more  BMCBI 2007»
14 years 9 months ago
Spatial location and its relevance for terminological inferences in bio-ontologies
Background: An adequate and expressive ontological representation of biological organisms and their parts requires formal reasoning mechanisms for their relations of physical aggr...
Stefan Schulz, Kornél G. Markó, Udo ...
BMCBI
2008
118views more  BMCBI 2008»
14 years 9 months ago
PseudoGeneQuest - Service for identification of different pseudogene types in the human genome
Background: Pseudogenes, nonfunctional copies of genes, evolve fast due the lack of evolutionary pressures and thus appear in several different forms. PseudoGeneQuest is an online...
Csaba P. Ortutay, Mauno Vihinen
BMCBI
2010
116views more  BMCBI 2010»
14 years 9 months ago
SEQADAPT: an adaptable system for the tracking, storage and analysis of high throughput sequencing experiments
Background: High throughput sequencing has become an increasingly important tool for biological research. However, the existing software systems for managing and processing these ...
David B. Burdick, Christopher C. Cavnor, Jeremy Ha...