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» Computing with Evolving Proteins
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CEC
2005
IEEE
15 years 3 months ago
Evolving hidden Markov models for protein secondary structure prediction
New results are presented for the prediction of secondary structure information for protein sequences using Hidden Markov Models (HMMs) evolved using a Genetic Algorithm (GA). We a...
Kyoung-Jae Won, Thomas Hamelryck, Adam Prügel...
EVOW
2004
Springer
15 years 1 months ago
Evolving Regular Expression-Based Sequence Classifiers for Protein Nuclear Localisation
A number of bioinformatics tools use regular expression (RE) matching to locate protein or DNA sequence motifs that have been discovered by researchers in the laboratory. For exam...
Amine Heddad, Markus Brameier, Robert M. MacCallum
EUROGP
2004
Springer
105views Optimization» more  EUROGP 2004»
15 years 3 months ago
Evolved Matrix Operations for Post-processing Protein Secondary Structure Predictions
Predicting the three-dimensional structure of proteins is a hard problem, so many have opted instead to predict the secondary structural state (usually helix, strand or coil) of e...
Varun Aggarwal, Robert M. MacCallum
EUROGP
2005
Springer
15 years 3 months ago
Evolving L-Systems to Capture Protein Structure Native Conformations
Abstract. A protein is a linear chain of amino acids that folds into a unique functional structure, called its native state. In this state, proteins show repeated substructures lik...
Gabi Escuela, Gabriela Ochoa, Natalio Krasnogor
BMCBI
2005
159views more  BMCBI 2005»
14 years 9 months ago
Columba: an integrated database of proteins, structures, and annotations
Background: Structural and functional research often requires the computation of sets of protein structures based on certain properties of the proteins, such as sequence features,...
Silke Trißl, Kristian Rother, Heiko Mül...