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» Computing with Evolving Proteins
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ICML
2006
IEEE
15 years 10 months ago
A graphical model for predicting protein molecular function
We present a simple statistical model of molecular function evolution to predict protein function. The model description encodes general knowledge of how molecular function evolve...
Barbara E. Engelhardt, Michael I. Jordan, Steven E...
BMCBI
2006
74views more  BMCBI 2006»
14 years 9 months ago
Protein protein interactions, evolutionary rate, abundance and age
Background: Does a relationship exist between a protein's evolutionary rate and its number of interactions? This relationship has been put forward many times, based on a biol...
Ramazan Saeed, Charlotte M. Deane
87
Voted
BMCBI
2005
119views more  BMCBI 2005»
14 years 9 months ago
The distance-profile representation and its application to detection of distantly related protein families
Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
Chin-Jen Ku, Golan Yona
ISMB
1994
14 years 11 months ago
Segmentation and Interpretation of 3D Protein Images
The segmentation and interpretation of threedimensionalimagesof proteins is considered. Atopological approachis used to represent a protein structure as a spanningtree of critical...
Laurence Leherte, Kim Baxter, Janice I. Glasgow, S...
ISMB
1993
14 years 11 months ago
A Modular Learning Environment for Protein Modeling
Wepropose in this paper a modularlearning environmentfor proteinmodeling.In this system,the protein modelingproblemis tackledin twosuccessive phases. First, partial structural inf...
Jérôme Gracy, Laurent Chiche, Jean Sa...