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BMCBI
2010
14 years 11 months ago
2010
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
BMCBI
2007
14 years 11 months ago
2007
Background: An adequate and expressive ontological representation of biological organisms and their parts requires formal reasoning mechanisms for their relations of physical aggr...
BMCBI
2007
2007
Missing channels in two-colour microarray experiments: Combining single-channel and two-channel data
14 years 11 months ago
Background: There are mechanisms, notably ozone degradation, that can damage a single channel of two-channel microarray experiments. Resulting analyses therefore often choose betw...
105
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BMCBI
2007
14 years 11 months ago
2007
Background: Peptide ligands have tremendous therapeutic potential as efficacious drugs. Currently, more than 40 peptides are available in the market for a drug. However, since cos...
103
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CGF
2008
14 years 11 months ago
2008
DNA microarrays are used to measure the expression levels of thousands of genes simultaneously. In a time series experiment, the gene expressions are measured as a function of tim...