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AEI
2006
108views more  AEI 2006»
14 years 11 months ago
Grammatical rules for specifying information for automated product data modeling
This paper presents a linguistic framework for developing a formal knowledge acquisition method. The framework is intended to empower domain experts to specify information require...
Ghang Lee, Charles M. Eastman, Rafael Sacks, Shamk...
BMCBI
2006
101views more  BMCBI 2006»
14 years 11 months ago
SuperMimic - Fitting peptide mimetics into protein structures
Background: Various experimental techniques yield peptides that are biologically active but have unfavourable pharmacological properties. The design of structurally similar organi...
Andrean Goede, Elke Michalsky, Ulrike Schmidt, Rob...
BMCBI
2006
169views more  BMCBI 2006»
14 years 11 months ago
Beyond microarrays: Finding key transcription factors controlling signal transduction pathways
Background: Massive gene expression changes in different cellular states measured by microarrays, in fact, reflect just an "echo" of real molecular processes in the cell...
Alexander E. Kel, Nico Voss, Ruy Jauregui, Olga V....
BMCBI
2006
102views more  BMCBI 2006»
14 years 11 months ago
Taking U out, with two nucleases?
Background: REX1 and REX2 are protein components of the RNA editing complex (the editosome) and function as exouridylylases. The exact roles of REX1 and REX2 in the editosome are ...
I. Saira Mian, Elizabeth A. Worthey, Reza Salavati
BMCBI
2006
114views more  BMCBI 2006»
14 years 11 months ago
Epigenetic acquisition of inducibility of type III cytotoxicity in P. aeruginosa
Background: Pseudomonas aeruginosa, an opportunistic pathogen, is often encountered in chronic lung diseases such as cystic fibrosis or chronic obstructive pneumonia, as well as a...
Didier Filopon, Annabelle Mérieau, Gilles B...
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