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ISMB
1994
15 years 3 months ago
Stochastic Motif Extraction Using Hidden Markov Model
In this paper, westudy the application of an ttMM(hidden Markov model) to the problem of representing protein sequencesby a stochastic motif. Astochastic protein motif represents ...
Yukiko Fujiwara, Minoru Asogawa, Akihiko Konagaya
HPDC
2010
IEEE
15 years 3 months ago
Detouring and replication for fast and reliable internet-scale stream processing
iFlow is a replication-based system that can achieve both fast and reliable processing of high volume data streams on the Internet scale. iFlow uses a low degree of replication in...
Christopher McConnell, Fan Ping, Jeong-Hyon Hwang
BMCBI
2010
114views more  BMCBI 2010»
15 years 2 months ago
An integrative modular approach to systematically predict gene-phenotype associations
Background: Complex human diseases are often caused by multiple mutations, each of which contributes only a minor effect to the disease phenotype. To study the basis for these com...
Michael R. Mehan, Juan Nunez-Iglesias, Chao Dai, M...
BMCBI
2006
109views more  BMCBI 2006»
15 years 2 months ago
A computational approach to discovering the functions of bacterial phytochromes by analysis of homolog distributions
Background: Phytochromes are photoreceptors, discovered in plants, that control a wide variety of developmental processes. They have also been found in bacteria and fungi, but for...
Tilman Lamparter
BMCBI
2006
103views more  BMCBI 2006»
15 years 2 months ago
Domain-based small molecule binding site annotation
Background: Accurate small molecule binding site information for a protein can facilitate studies in drug docking, drug discovery and function prediction, but small molecule bindi...
Kevin A. Snyder, Howard J. Feldman, Michel Dumonti...