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ISMB
1994
14 years 11 months ago
Stochastic Motif Extraction Using Hidden Markov Model
In this paper, westudy the application of an ttMM(hidden Markov model) to the problem of representing protein sequencesby a stochastic motif. Astochastic protein motif represents ...
Yukiko Fujiwara, Minoru Asogawa, Akihiko Konagaya
HPDC
2010
IEEE
14 years 11 months ago
Detouring and replication for fast and reliable internet-scale stream processing
iFlow is a replication-based system that can achieve both fast and reliable processing of high volume data streams on the Internet scale. iFlow uses a low degree of replication in...
Christopher McConnell, Fan Ping, Jeong-Hyon Hwang
BMCBI
2010
114views more  BMCBI 2010»
14 years 10 months ago
An integrative modular approach to systematically predict gene-phenotype associations
Background: Complex human diseases are often caused by multiple mutations, each of which contributes only a minor effect to the disease phenotype. To study the basis for these com...
Michael R. Mehan, Juan Nunez-Iglesias, Chao Dai, M...
BMCBI
2006
109views more  BMCBI 2006»
14 years 10 months ago
A computational approach to discovering the functions of bacterial phytochromes by analysis of homolog distributions
Background: Phytochromes are photoreceptors, discovered in plants, that control a wide variety of developmental processes. They have also been found in bacteria and fungi, but for...
Tilman Lamparter
BMCBI
2006
103views more  BMCBI 2006»
14 years 10 months ago
Domain-based small molecule binding site annotation
Background: Accurate small molecule binding site information for a protein can facilitate studies in drug docking, drug discovery and function prediction, but small molecule bindi...
Kevin A. Snyder, Howard J. Feldman, Michel Dumonti...