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» Connecting Genes with Diseases
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BMCBI
2006
249views more  BMCBI 2006»
14 years 9 months ago
Gene functional similarity search tool (GFSST)
Background: With the completion of the genome sequences of human, mouse, and other species and the advent of high throughput functional genomic research technologies such as biomi...
Peisen Zhang, Jinghui Zhang, Huitao Sheng, James J...
BMCBI
2008
97views more  BMCBI 2008»
14 years 9 months ago
MCM-test: a fuzzy-set-theory-based approach to differential analysis of gene pathways
Background: Gene pathway can be defined as a group of genes that interact with each other to perform some biological processes. Along with the efforts to identify the individual g...
Lily R. Liang, Vinay Mandal, Yi Lu, Deepak Kumar
BMCBI
2008
129views more  BMCBI 2008»
14 years 9 months ago
Mining phenotypes for gene function prediction
Background: Health and disease of organisms are reflected in their phenotypes. Often, a genetic component to a disease is discovered only after clearly defining its phenotype. In ...
Philip Groth, Bertram Weiss, Hans-Dieter Pohlenz, ...
BMCBI
2010
132views more  BMCBI 2010»
14 years 9 months ago
Error margin analysis for feature gene extraction
Background: Feature gene extraction is a fundamental issue in microarray-based biomarker discovery. It is normally treated as an optimization problem of finding the best predictiv...
Chi Kin Chow, Hai Long Zhu, Jessica Lacy, Winston ...
BMCBI
2011
14 years 4 months ago
Pathway-based analysis using reduced gene subsets in genome-wide association studies
Background: Single Nucleotide Polymorphism (SNP) analysis only captures a small proportion of associated genetic variants in Genome-Wide Association Studies (GWAS) partly due to s...
Jingyuan Zhao, Simone Gupta, Mark Seielstad, Jianj...