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» Connecting Genes with Diseases
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BMCBI
2006
118views more  BMCBI 2006»
14 years 12 months ago
Djinn Lite: a tool for customised gene transcript modelling, annotation-data enrichment and exploration
Background: There is an ever increasing rate of data made available on genetic variation, transcriptomes and proteomes. Similarly, a growing variety of bioinformatic programs are ...
Erdahl T. Teber, Edward Crawford, Kent B. Bolton, ...
BMCBI
2004
189views more  BMCBI 2004»
14 years 11 months ago
B.E.A.R. GeneInfo: A tool for identifying gene-related biomedical publications through user modifiable queries
Background: Once specific genes are identified through high throughput genomics technologies there is a need to sort the final gene list to a manageable size for validation studie...
Guohui Zhou, Xinyu Wen, Hang Liu, Michael J. Schli...
BMCBI
2006
138views more  BMCBI 2006»
14 years 12 months ago
Determination of strongly overlapping signaling activity from microarray data
Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...
Ghislain Bidaut, Karsten Suhre, Jean-Michel Claver...
BMCBI
2010
196views more  BMCBI 2010»
14 years 9 months ago
Content-based microarray search using differential expression profiles
Background: With the expansion of public repositories such as the Gene Expression Omnibus (GEO), we are rapidly cataloging cellular transcriptional responses to diverse experiment...
Jesse M. Engreitz, Alexander A. Morgan, Joel Dudle...
BMCBI
2010
97views more  BMCBI 2010»
14 years 6 months ago
A semi-parametric Bayesian model for unsupervised differential co-expression analysis
Background: Differential co-expression analysis is an emerging strategy for characterizing disease related dysregulation of gene expression regulatory networks. Given pre-defined ...
Johannes M. Freudenberg, Siva Sivaganesan, Michael...