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BIOCOMP
2006
15 years 1 months ago
Computational Inference of Compound-induced Anti-inflammatory Effects Across Time in an Adjuvant-induced Arthritis Rat Model
A number of diseases, such as arthritis and cardiovascular disorders impacting the lives of many people have strong inflammatory components. To elucidate the antiinflammatory mecha...
Jing Yu, Gabriel Helmlinger, Muriel Saulnier, Anna...
TCBB
2008
116views more  TCBB 2008»
14 years 11 months ago
Inferring Connectivity of Genetic Regulatory Networks Using Information-Theoretic Criteria
Recently, the concept of mutual information has been proposed for inferring the structure of genetic regulatory networks from gene expression profiling. After analyzing the limitat...
Wentao Zhao, Erchin Serpedin, Edward R. Dougherty
KDD
2004
ACM
145views Data Mining» more  KDD 2004»
16 years 6 days ago
Mining coherent gene clusters from gene-sample-time microarray data
Extensive studies have shown that mining microarray data sets is important in bioinformatics research and biomedical applications. In this paper, we explore a novel type of genesa...
Daxin Jiang, Jian Pei, Murali Ramanathan, Chun Tan...
BMCBI
2008
127views more  BMCBI 2008»
14 years 12 months ago
Gene and pathway identification with Lp penalized Bayesian logistic regression
Background: Identifying genes and pathways associated with diseases such as cancer has been a subject of considerable research in recent years in the area of bioinformatics and co...
Zhenqiu Liu, Ronald B. Gartenhaus, Ming Tan, Feng ...
BMCBI
2006
183views more  BMCBI 2006»
14 years 12 months ago
Mining gene expression data by interpreting principal components
Background: There are many methods for analyzing microarray data that group together genes having similar patterns of expression over all conditions tested. However, in many insta...
Joseph C. Roden, Brandon W. King, Diane Trout, Ali...