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BMCBI
2005
153views more  BMCBI 2005»
14 years 11 months ago
Mining published lists of cancer related microarray experiments: Identification of a gene expression signature having a critical
Background: Routine application of gene expression microarray technology is rapidly producing large amounts of data that necessitate new approaches of analysis. The analysis of a ...
Giacomo Finocchiaro, Francesco Mancuso, Heiko M&uu...
BIOCOMP
2006
15 years 1 months ago
Finding Molecular Signature of Prostate Cancer: An Algorithmic Approach
123 African American men in America are 65% more likely to develop prostate cancer and are two to three times more likely to die of the disease than Caucasian men [1]. While resear...
Patrick Bobbie, Renee Reams, Sandra Suther, C. Per...
ITA
2006
167views Communications» more  ITA 2006»
14 years 11 months ago
Characterization of lung tumor subtypes through gene expression cluster validity assessment
The problem of assessing the reliability of clusters patients identified by clustering algorithms is crucial to estimate the significance of subclasses of diseases detectable at b...
Giorgio Valentini, Francesca Ruffino
BMCBI
2008
77views more  BMCBI 2008»
14 years 12 months ago
A simple and robust method for connecting small-molecule drugs using gene-expression signatures
Background: Interaction of a drug or chemical with a biological system can result in a geneexpression profile or signature characteristic of the event. Using a suitably robust alg...
Shu-Dong Zhang, Timothy W. Gant
VLDB
2004
ACM
143views Database» more  VLDB 2004»
15 years 5 months ago
GPX: Interactive Mining of Gene Expression Data
Discovering co-expressed genes and coherent expression patterns in gene expression data is an important data analysis task in bioinformatics research and biomedical applications. ...
Daxin Jiang, Jian Pei, Aidong Zhang