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» Connecting Genes with Diseases
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BMCBI
2006
216views more  BMCBI 2006»
14 years 12 months ago
Machine learning approaches to supporting the identification of photoreceptor-enriched genes based on expression data
Background: Retinal photoreceptors are highly specialised cells, which detect light and are central to mammalian vision. Many retinal diseases occur as a result of inherited dysfu...
Haiying Wang, Huiru Zheng, David Simpson, Francisc...
BMCBI
2002
195views more  BMCBI 2002»
14 years 11 months ago
Clustering of the SOM easily reveals distinct gene expression patterns: results of a reanalysis of lymphoma study
Background: A method to evaluate and analyze the massive data generated by series of microarray experiments is of utmost importance to reveal the hidden patterns of gene expressio...
Junbai Wang, Jan Delabie, Hans Christian Aasheim, ...
BMCBI
2010
143views more  BMCBI 2010»
14 years 12 months ago
Learning gene regulatory networks from only positive and unlabeled data
Background: Recently, supervised learning methods have been exploited to reconstruct gene regulatory networks from gene expression data. The reconstruction of a network is modeled...
Luigi Cerulo, Charles Elkan, Michele Ceccarelli
SDM
2008
SIAM
157views Data Mining» more  SDM 2008»
15 years 1 months ago
ROC-tree: A Novel Decision Tree Induction Algorithm Based on Receiver Operating Characteristics to Classify Gene Expression Data
Gene expression information from microarray experiments is a primary form of data for biological analysis and can offer insights into disease processes and cellular behaviour. Suc...
M. Maruf Hossain, Md. Rafiul Hassan, James Bailey
IJBRA
2008
66views more  IJBRA 2008»
14 years 12 months ago
Integer programming-based approach to allocation of reporter genes for cell array analysis
Abstract Observing behaviors of protein pathways and genetic networks under various environments in living cells is essential for unraveling disease and developing drugs. For that ...
Morihiro Hayashida, Fuyan Sun, Sachiyo Aburatani, ...